Evidence lights the way

Centrosome Maturation: Aurora Lights the Way to the Poles

The centrosome is the main microtubule organising centre in the cell. During mitosis, centrosomes dramatically increase microtubule nucleating activity, enabling them to form a mitotic spindle. Recent studies show that Aurora A kinase promotes microtubule assembly from centrosomes through the phosphorylation of the conserved centrosomal protein TACC.

Pax6 lights-up the way for eye development.

Recent reports have exposed the temporal and spatial functions of the transcription factor Pax6 in the developing vertebrate eye. Pax6 is demonstrated to play essential roles in successive steps triggering lens differentiation while in the retina it functions to maintain multipotency and proliferation of retinal progenitor cells. These findings, together with the identification of Pax6 protein ...

the way toward evidence based nursing

Guiding Lights - Facilitation of Way-finding for People with Dementia via Spatial Light Cues

The percentage of People with Dementia (PwD) in residential nursing homes is increasing. PwD are facing difficulties in their daily activities, including way-finding. In this paper, we propose light cues as a solution for supporting PwD in orientation and way-finding in the facilities. A study on a spatial searching task with four participants was conducted. Preliminary results indicate a stron...

Arbour lights

Amongst the theoreticians there was a subspecies who interacted with experimentalists — these theorists tried to make sure that their ideas were testable and that someone tested them. Preeminent amongst these was Francis Crick who wrote all the quotes above shown in red italics (taken from Crick’s autobiographical book What Mad Pursuit: A Personal View of Scientific Discovery; Basic Books, New ...